1-(3-BROMOPHENYL)TETRAHYDRO-2H-IMIDAZOL-2-ONE is an organic compound with the chemical formula C10H9BrN2O. The following is a description of the relevant Properties, Uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystal or crystalline powder
-Melting point: About 120-123 degrees Celsius
-Insoluble in water, soluble in organic solvents such as alcohol and ether
-Stable in the air, but avoid moisture and exposure to strong light
-May cause irritation and allergic reactions to human body, use with caution
Use:
1-(3-BROMOPHENYL)TETRAHYDRO-2H-IMIDAZOL-2-ONE is an important intermediate compound, which has a wide range of applications in the field of organic synthesis and drug research and development. It is mainly used in the synthesis of other organic compounds and drugs, such as anti-cancer drugs and anti-inflammatory drugs.
Method:
The preparation of 1-(3-BROMOPHENYL)TETRAHYDRO-2H-IMIDAZOL-2-ONE is usually carried out by the following steps:
1. Reacting benzene or p-bromotoluene with cyanoethane under alkaline conditions to prepare 3-bromobenzylacetic acid;
2. Reacting 3-bromobenzeneacetic acid with iminoimidazole under alkaline conditions to produce 1-(3-bromophenyl)-2-imidazolyl acetic acid;
3. Acidolysis or decarboxylation of 1-(3-BROMOPHENYL)-2-imidazole acetic acid under acidic conditions to obtain the final product 1-(3-BROMOPHENYL)TETRAHYDRO-2H-IMIDAZOL-2-ONE.
Safety Information:
- 1-(3-BROMOPHENYL)TETRAHYDRO-2H-IMIDAZOL-2-ONE is a chemical that requires compliance with relevant safe handling and personal protective measures;
-contact with skin, eyes and respiratory tract should be avoided, if contact occurs, immediately rinse with water and seek medical help;
-It should be used in a well-ventilated place and avoid inhaling its dust or vapor;
-Avoid contact with oxidants and strong acids during use to avoid dangerous reactions;
-Compliance with regulations and accurate labeling of chemicals during storage and handling.